Mechanisms
Mechanisms
* Low FiO2
Relative (inadequate for patient’s condition)
Absolute (problems delivering O2 to circuit)
* Inadequate VA
* V/Q mismatch
* Anatomic shunt
* Excess metabolic O2 demand
* Low cardiac output
* Low FiO2
Relative (inadequate for patient’s condition)
Absolute (problems delivering O2 to circuit)
* Inadequate VA
* V/Q mismatch
* Anatomic shunt
* Excess metabolic O2 demand
* Low cardiac output
Clinical Causes
Clinical Causes
* Inadequate ventilation
AIRWAY obstruction
HYPOVENTILATION during GA
* Endobronchial intubation
* Patients with increased A-a gradient
Pre-existing lung disease
>Pneumothorax
Pulmonary edema
Aspiration
Atelectasis
Pulmonary embolism
* Low cardiac output
* Inadequate ventilation
AIRWAY obstruction
HYPOVENTILATION during GA
* Endobronchial intubation
* Patients with increased A-a gradient
Pre-existing lung disease
>Pneumothorax
Pulmonary edema
Aspiration
Atelectasis
Pulmonary embolism
* Low cardiac output
Prevention
Prevention
* Check anaesthetic machine
O2 analyser & alarms
* Adequate Ventilation (esp tidal volume)
* Monitor & adjust FiO2
* High normal range tidal volume
* Caution with spontaneous ventilation in lung disease
* Check anaesthetic machine
O2 analyser & alarms
* Adequate Ventilation (esp tidal volume)
* Monitor & adjust FiO2
* High normal range tidal volume
* Caution with spontaneous ventilation in lung disease
Manifestations
Manifestations
* Pulse Oximetry
Malfunction can occur: check waveform & probe position
o Hypothermia
o Poor peripheral circulation
o Artifacts: diathermy, motion, ambient lighting
o Dyes
o Cyanosis
o Dark blood in surgical field
o Late signs
bradycardia , myocardial ischaemia & dysrhythmias, hypotension and cardiac arrest
* Pulse Oximetry
Malfunction can occur: check waveform & probe position
o Hypothermia
o Poor peripheral circulation
o Artifacts: diathermy, motion, ambient lighting
o Dyes
o Cyanosis
o Dark blood in surgical field
o Late signs
bradycardia , myocardial ischaemia & dysrhythmias, hypotension and cardiac arrest
Management
Management
* Assume low SpO2 = hypoxaemia
* Increase FiO2
Verify FiO2 increases
* Check pulse, BP
* Check EtCO2 & pulse oximeter (refer next slide)
* Hand ventilate - assess lung compliance, give large TV
* Check chest movements & auscultate chest
Exclude endobronchial intubation
* ABG’s
* Posture sitting up
* Assume low SpO2 = hypoxaemia
* Increase FiO2
Verify FiO2 increases
* Check pulse, BP
* Check EtCO2 & pulse oximeter (refer next slide)
* Hand ventilate - assess lung compliance, give large TV
* Check chest movements & auscultate chest
Exclude endobronchial intubation
* ABG’s
* Posture sitting up
Verify Pulse Oximeter
Verify Pulse Oximeter
* do not fixate
Assess signal amplitude
Check waveform
Check position
Correlate reading with diathermy
Shield probe
Change site
* do not fixate
Assess signal amplitude
Check waveform
Check position
Correlate reading with diathermy
Shield probe
Change site
Persistent hypoxemia causes
Persistent hypoxemia causes
* Pulmonary
Pneumothorax - consider CXR
Aspiration
Massive atelectasis
Pulmonary embolism
Aspiration of foreign body
Acute pulmonary oedema
* Extra-Pulmonary
Low cardiac output
Low Hb
Intracardiac shunting in CHD
* Pulmonary
Pneumothorax - consider CXR
Aspiration
Massive atelectasis
Pulmonary embolism
Aspiration of foreign body
Acute pulmonary oedema
* Extra-Pulmonary
Low cardiac output
Low Hb
Intracardiac shunting in CHD
Persistent hypoxemia management
Persistent hypoxemia management
* Use aggressive pulmonary toilet
Suction ETT
Consider bronchoscopy
* Consider addition of PEEP
Maintain large tidal volume 12-15ml/kg
* Restore circulating blood volume
Maintain CO and Hb levels (Hb>100g/L)
Consider inotropes
* Use aggressive pulmonary toilet
Suction ETT
Consider bronchoscopy
* Consider addition of PEEP
Maintain large tidal volume 12-15ml/kg
* Restore circulating blood volume
Maintain CO and Hb levels (Hb>100g/L)
Consider inotropes
Unresolved hypoxemia
Unresolved hypoxemia
* Inform surgeons (earlier if appropriate)
Check retractors
Transfer to supine position
Terminate surgery ASAP
* Investigations in PACU
Incl. CXR, ABG’s
* Arrange transfer to ICU
* Inform surgeons (earlier if appropriate)
Check retractors
Transfer to supine position
Terminate surgery ASAP
* Investigations in PACU
Incl. CXR, ABG’s
* Arrange transfer to ICU
Awake patient
Awake patient
* Detection see previous slide
* Look for cause
Inadequate Ventilation airway, depressed VA
Pulmonary and extra-pulmonary
Also diffusion hypoxaemia, laryngospasm, inadequate reversal, shivering
* Management
High flow O2 - CPAP - re-intubation
Drug reversal relaxants, opioids
* Detection see previous slide
* Look for cause
Inadequate Ventilation airway, depressed VA
Pulmonary and extra-pulmonary
Also diffusion hypoxaemia, laryngospasm, inadequate reversal, shivering
* Management
High flow O2 - CPAP - re-intubation
Drug reversal relaxants, opioids